Chapter 01: Orientation to Pharmacology
Burchum: Lehne’s Pharmacology for Nursing Care, 11th Edition

MULTIPLE CHOICE

	1.	The nurse is teaching a patient how a medication works to treat an illness. To do this, the nurse will rely on knowledge of which topic?
a.	Clinical pharmacology	
b.	Drug efficacy	
c.	Pharmacokinetics	
d.	Pharmacotherapeutics	

ANS:	D
Pharmacotherapeutics is the study of the use of drugs to diagnose, treat, and prevent conditions. Clinical pharmacology is concerned with all aspects of drug-human interactions. Drug efficacy measures the extent to which a given drug causes an intended effect. Pharmacokinetics is the study of the impact of the body on a drug.

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	2.	What is a desired outcome when a drug is described as easy to administer?
a.	It can be stored indefinitely without need for refrigeration.	
b.	It does not interact significantly with other medications.	
c.	It enhances patient adherence to the drug regimen.	
d.	It is usually relatively inexpensive to produce.	

ANS:	C
A major benefit of drugs that are easy to administer is that patients taking them are more likely to comply with the drug regimen. Drugs that are easy to give may have the other attributes listed, but those properties are independent of ease of administration.

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	3.	A patient tells the nurse that an analgesic he will begin taking may cause drowsiness and will decrease pain up to 4 hours at a time. Based on this understanding of the drug’s effects by the patient, the nurse will anticipate which outcome?
a.	Decreased chance of having a placebo effect	
b.	Decreased motivation to take the drug	
c.	Improved compliance with the drug regimen	
d.	Increased likelihood of drug overdose	

ANS:	C
A drug is effective if it produces the intended effects, even if it also produces side effects. Patients who understand both the risks and benefits of taking a medication are more likely to comply with the drug regimen.

PTS:	1

MULTIPLE RESPONSE

	1.	What are considered the ‘Big Three’ properties of an ideal drug? (Select all that apply.)
a.	Irreversible action	
b.	Effectiveness	
c.	Safety	
d.	Selectivity	
e.	A recognizable trade name	

ANS:	B, C, D
The ‘Big Three’ properties of the ideal drug are effectiveness, safety, and selectivity.

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	2.	Before administering a medication, what does the nurse need to know to evaluate how individual patient variability might affect the patient’s response to the medication? (Select all that apply.)
a.	Chemical stability of the medication	
b.	Ease of administration	
c.	Family medical history	
d.	Patient’s age	
e.	Patient’s diagnosis	

ANS:	C, D, E
The family medical history can indicate genetic factors that may affect a patient’s response to a medication. Patients of different ages can respond differently to medications. The patient’s illness can affect how drugs are metabolized. The chemical stability of the medication and the ease of administration are properties of drugs.

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